CALMIVET 20 Tablets | Antiemetic, tranquilizer and sedative in tablets

CALMIVET TABLETS Antiemetic, tranquilizer and sedative in tablets

Laboratory
VETOQUINOL EVSA
Pharmaceutical form
Oral tablet (Comp.o.)
Composition:
Acepromazine maleate 17 mg (equivalent to 12,5 mg acepromazine base). Excipient qs for
1 tablet.
Pharmacological properties
Pharmacological properties: The active substance in Calmivet, acepromazine, belongs to the group of
the phenothiazines. Phenothiazines have a depressant action on the central nervous system.
This action is probably linked in part to receptor antagonism.
dopaminergic. Therefore, phenothiazines are used as neuroleptics and antiemetics.
The depth of sedation is dose dependent and can vary greatly from one individual to another.
Its antagonistic effect on adrenergic receptors can cause hypotension.
Pharmacokinetics: With the usual recommended doses, the sedative effect lasts for 4
to 8 hours, although it can be extended up to 12 hours depending on the individual. They are more doses
elevated, sedation is prolonged without increasing its depth.
Interactions and incompatibilities
The depressant effect of Calmivet increases in case of simultaneous administration of other central depressants (morphines, barbiturates, xylazine, etc.). Antihypertensives may potentiate the hypotensive effect of Calmivet.
Do not administer to animals undergoing treatment with organophosphates as they enhance their toxic effects.
Indications and target species
Dogs y Cats: Tranquilizer, sedative, antiemetic whenever the cause is vomiting due to motion sickness.
Contraindications
• Hypovolemic hypotension.
• Decompensated heart failure.
• Skin allergy test (inhibition of histamine H1 receptors).
• Allergy to phenothiazines.
• Epilepsy.
• Pregnancy and lactation.
• Contraindicated in cats with liver failure due to the hepatotoxic nature of the specialty.
in this species.
efectos secundarios
In general, cats have more adverse effects and more frequently than dogs.
Thus, the most frequent adverse reactions that can appear in both species are:
• Hypothermia, hypotension (which will cause reflex tachycardia and weak pulse), slight increase in
heart rate, hyperglycemia, thrombocytopenia and/or platelet dysfunction, fainting, and collapse
cardiovascular disease, vomiting, anxiolysis and profound depression in dogs (with daily doses greater than 10
mg/kg).
In addition, in cats it can appear:
• Significantly decreased motor activity, hyperactivity and aggression (even at low doses),
signs of analgesia (at high doses), sphincter relaxation, polydipsia, excitement, disturbances
digestive, and penile prolapse.
Route of administration
Orally.
Posology
Dogs: Antiemetic and tranquilizer: 0,75 tablets/10 kg.
Sedative: 1,5 to 3 tablets/10 kg.
Cats: Antiemetic: 1,2 tablets/10 kg. Soothing: 0,75 to 1,5 tablets/10 kg.
Sedative: 1,5 tablets/10 kg.
• Calmivet Tablets should be administered 1 hour before the trip or stressful situation and can
repeat administration 6 hours later.
• The presence or absence of effect is detected by the existence or absence of profusion of the
nictitating membrane.
• The maximum recommended dose is 5 mg/kg in dogs (equivalent to 3 tablets/10 kg body weight).
live) and 2,5 mg/kg in cats (equivalent to 1,5 tablets/10 kg of live weight).
overdose: An increase in dose may cause excitation, extrapyramidal symptoms such as
such as tremor and catalepsy, as well as depression of the cardiorespiratory system.
• The cat is much more sensitive than the dog to overdose.
• In case of massive ingestion of Calmivet, gastric lavage must be performed. The treatment will be
symptomatic (cardiorespiratory intensive care).
Special precautions
Use during pregnancy and lactation: Due to the absence of data referring to the effect of
drug on the fetus and its passage into milk, it is advisable not to administer Calmivet in animals in
pregnant or lactating.
Wait time
Not applicable.
conservation mode
Expiration once the container is opened: 24 months.
Comments
With veterinary prescription.
Presentation
Container of 20 tablets.
Reg No.
1225 ESP

See technical sheet

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