ATOPICA 100 MG 30 CAPSULES | CHRONIC ALLERGIC DERMATITIS IN DOGS

Category:

Dermatological, non-steroidal anti-inflammatory and antipruritic in soft capsules.

Laboratory: Novartis Animal Health SL

Composition per Capsule:

• Atopica® 25 mg: Cyclosporine 25 mg.
• Atopica® 50 mg: Cyclosporine 50 mg.
• Atopica® 100 mg: Cyclosporine 100 mg.

Indications and Use

Target Species:

Dogs.

Therapeutic Indication:

• Treatment of manifestations of chronic atopic dermatitis, including persistent itching and inflammation of the skin.

Dosage and Administration

Recommended dose:

5 mg/kg of body weight . Administer the capsule directly into the dog's mouth at least 2 hours before or after meals.

Treatment Scheme:

1. Early stage:
   Administer daily until clinical improvement is observed (normally in 4 weeks). If there is no improvement in 8 weeks, discontinue treatment.
2. Maintenance:
   • Reduce the frequency of administration to alternate days.
   • In some cases, dosing may be every 3-4 days.
3. Restarting Treatment:
   • If symptoms recur, resume daily treatment.
   • Some pets may require consecutive cycles of treatment.

Additional Recommendation:

To improve results, consider complementary treatments such as medicated shampoos and essential fatty acid supplements.

Contraindications:

• Do not use on:
  • Dogs under 18 years old 6 months or with weight less than 2 kg.
  • Animals with a history of malignant tumors.
  • Cases of hypersensitivity to cyclosporine or its excipients.
  • Vaccination with live vaccines during treatment or 2 weeks before/after.

Drug Interactions:

• Cyclosporine levels increase:
  • Ketoconazole (increases up to 5 times).
  • Erythromycin (doubles plasma levels).
• Reduce cyclosporine levels:
  • Anticonvulsants and antibiotics such as trimethoprim/sulfadimidine.
• Caution with:
  • Macrocyclic lactones (eg, ivermectin, milbemycin) due to risk of CNS toxicity.
  • Aminoglycoside antibiotics and trimethoprim due to possible nephrotoxicity.

Note: Dosage adjustment based on veterinary evaluation.

Side effects:

• Frequent:
  • Vomiting, diarrhea, loose or mucous stools (mild and transient).
• Less Common:
  • Lethargy, hyperactivity, anorexia.
  • Gingival hyperplasia (mild to moderate).
  • Changes in coat, wart-like lesions.
  • Redness and swelling of the earlobe.
• Rare Reactions:
  • Lymphadenopathy, muscle cramps.

In case of persistent or severe adverse reactions, consult your veterinarian.

Special Precautions

In Animals:

• Confirm diagnosis and rule out other causes of dermatitis (eg, food allergy, flea infestations).
• Monitor for bacterial and fungal infections before and during treatment.
• Monitor for lymphadenopathy or signs of renal failure in severe cases.
• Avoid use in diabetic dogs.

In People:

• Wash hands after administration.
• Avoid direct contact with the capsules if you are pregnant.
• In case of accidental ingestion, seek immediate medical attention.

Conservation Mode:

• Store at a temperature below 25 °C.
• Keep the capsules in the blister inside the original packaging.

Frequently Asked Questions (FAQs)

1. How long does it take for Atopica® to take effect?
Symptoms usually improve within 15 days. first 4 weeks.

2. Can I use Atopica® together with other medications?
Consult your veterinarian due to possible drug interactions.

3. Is it safe for long-term use?
Yes, under veterinary supervision. The dosage should be adjusted according to the dog's response.

4. What should I do if my dog ​​is vomiting?
This is a common side effect. Continue treatment and consult your veterinarian if it persists.

Available presentations:

• Atopica® 25 mg: Boxes with 30 capsules (Dogs from 4 to 7.5 kg).
• Atopica® 50 mg: Boxes with 30 capsules (Dogs from 7.5 to 36 kg).
• Atopica® 100 mg: Boxes with 30 capsules (Dogs from 15 to 55 kg).

Key Benefits:

• Effective in the management of chronic atopic dermatitis.
• Formula adapted to different sizes of dogs.
• Proven safety for long-term treatment under veterinary supervision.

Consult your veterinarian for more information and personalized treatment with Atopica®.