DEXABIOPEN 100ML | ANTI-INFLAMMATORY FOR SHEEP, EQUINE, BOVINE AND PIG

DEXABIOPEN 

Antibacterial and anti-inflammatory steroid in injectable suspension

Laboratory

SYVA

Pharmaceutical form

Injectable suspension (Susp.i.)

Composition per ml:

Procaine benzylpenicillin 200000 IU; dihydrostreptomycin 200 mg; dexamethasone 0,50 mg.

Interactions and incompatibilities

Do not administer together with:

• Bacteriostatic antibiotics and other aminoglycosides, due to their antagonism.
• Sulfonamides, since procaine could reduce their activity.
• Pentobarbital and inhalation anesthetics, due to the risk of vascular depression.
• Muscle relaxants, due to the risk of neuromuscular blockade.
• Diuretics, due to the risk of increasing ototoxicity.

Indications

Infections caused by microorganisms sensitive to benzylpenicillin and dihydrostreptomycin and presenting with acute inflammation:

Cattle: Treatment of respiratory infections caused by Pasteurella multocida.

Pigs: Treatment of respiratory infections caused by Actinobacillus pleuropneumoniae and/or Pasteurella multocida; meningitis caused by Stretococcus suis, Listeria

monocytogenes and/or Haemophilus parasuis; Glässer's disease caused by Haemophilus parasuis.

Contraindications

Do not use in animals with:

• Hypersensitivity to some of its components
• Viral and/or fungal infections.
• Known allergies to ester-type local anesthetics, due to possible allergic effect

crusades.

• Kidney failure, liver disease, heart disease or cochlear-vestibular lesions.
• Osteoporosis and/or bone fractures.
• Mellitus diabetes.
• Degenerative ocular diseases or corneal ulcers.
• Hyperadrenocorticism.
• Age less than 1 month.
• In rabbits, guinea pigs and hamsters.
• Animals subjected to immunological treatment.

Adverse reactions

• Penicillins can cause allergic or anaphylactic reactions in hypersensitive animals, particularly cattle, causing salivation, fever, vomiting, dyspnea, incoordination, tremors, and skin reactions such as angioedema and urticaria. In severe cases, treatment should be stopped and emergency treatment applied (epinephrine and/or corticosteroids).

• Aminoglycosides can cause nephrotoxicity, ototoxicity, and neuromuscular blockade in all species.
• Dexamethasone can mask the signs of infection (pyrexia, loss of appetite, etc.).
• Decreases organic defenses and delays wound healing.
• Procaine, administered intramuscularly, can produce a mild excitatory reaction.
• Intravenously it can cause changes in behavior and locomotion and/or vascular changes. In none of these cases were the adverse reactions serious.

• This drug may also cause mild transient local reactions at the injection site.

• In piglets and fattening pigs, occasionally and in stressful situations, transient fever, vomiting, incoordination, tremors and apathy can occur.

Route of administration

Deep intramuscular.

Posology

Cattle and Pigs: 1 ml/10 20 kg bw per day, for three days.

Special precautions

• Do not handle the medicine if you are allergic to penicillins, cephalosporins or other components of the medicine.

• Do not administer for more than 3 consecutive days, subsequently continuing treatment with antibiotics without corticosteroids.

Use during pregnancy or lactation:

• Do not administer during the last third of pregnancy.

have waiting time

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Wait time

Meat:

Cattle: 56 days.

Pigs: 68 days.

Milk: 60 hours.

Comments

With veterinary prescription.

Veterinary prescription required Yes

DEXABIOPEN