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HomeShop › PRILBEN VET 5 MG 14 COMPRIMIDOS | TRATMIENTO DE LA INSUFICIENCIA CARDIACA EN PERROS
PRILBEN VET 5 MG 14 COMPRIMIDOS | TRATMIENTO DE LA INSUFICIENCIA CARDIACA EN PERROS
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PRILBEN VET 5 mg Tablets for Canine Heart Failure

Reduces peripheral resistance and left ventricular load in dogs with heart failure.

★★★★★ 4.00 (90 reviews)
E20.84
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PRILBEN VET 5 mg is indicated for the treatment of heart failure in dogs. It contains benazepril hydrochloride, a prodrug that is hydrolyzed in vivo to the active metabolite benazeprilat. Benazeprilat inhibits angiotensin converting enzyme (ACE), preventing the conversion of inactive angiotensin I to active angiotensin II. This inhibition reduces arterial and venous vasoconstriction and decreases sodium and water retention by the kidneys.

In dogs with heart failure, benazepril hydrochloride reduces peripheral resistance, blood pressure, and left ventricular load. After oral administration, benazepril is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations of benazeprilat are reached within approximately 2 hours, regardless of food intake. The absolute systemic bioavailability is about 9%.

Repeated administration leads to slight accumulation of benazeprilat in plasma, reaching steady state in less than 4 days. In dogs, most benazeprilat is eliminated rapidly, with equal excretion via hepatic and urinary routes. After a single dose of 0.23 mg benazepril/kg body weight, the peak concentration of benazeprilat is 40.9 ng/ml, reached at 1.5 hours, with an AUC of 320.5 ng/ml/h and a half life of 12.4 hours.

Active Ingredients

Each tablet contains benazepril 4.6 mg, equivalent to 5 mg of benazepril hydrochloride. Excipients include titanium dioxide (E171), yellow iron oxide (E172), red iron oxide (E172), and black iron oxide (E172).

Indications

PRILBEN VET 5 mg is used for the treatment of heart failure in dogs. It is a film coated tablet for oral administration in dogs and cats.

Dosing Guide

Follow your veterinarian's prescription.

Storage

Store as directed on packaging.

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Frequently Asked Questions — PRILBEN VET 5 MG 14 COMPRIMIDOS | TRATMIENTO DE LA INSUFICIENCIA CARDIACA EN PERROS