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HomeShop › PRILBEN VET 20 MG 14 COMPRIMIDOS | TRATMIENTO DE LA INSUFICIENCIA CARDIACA EN PERROS
PRILBEN VET 20 MG 14 COMPRIMIDOS | TRATMIENTO DE LA INSUFICIENCIA CARDIACA EN PERROS
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PRILBEN VET 20 mg for Canine Heart Failure Treatment

Reduces peripheral resistance and left ventricular load in dogs with heart failure.

★★★★★ 3.99 (85 reviews)
E24.88
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PRILBEN VET 20 mg is indicated for the treatment of heart failure in dogs. The active substance benazepril hydrochloride is a prodrug that is hydrolyzed in vivo to benazeprilat, which inhibits angiotensin converting enzyme (ACE). This prevents conversion of inactive angiotensin I to active angiotensin II, thereby blocking vasoconstriction and sodium and water retention.

Benazeprilat causes prolonged inhibition of plasma ACE in dogs, persisting significantly for 24 hours after a single dose. In dogs with heart failure, it reduces peripheral resistance, blood pressure, and left ventricular load. After oral administration, benazepril is rapidly absorbed from the gastrointestinal tract. Peak benazeprilat concentrations occur at approximately 2 hours, both with and without food. Absolute systemic bioavailability is about 9%.

Steady state is reached in less than 4 days. After a single dose of 0.23 mg benazepril per kg body weight, peak benazeprilat concentration is 40.9 ng/ml at 1.5 hours, with an AUC of 320.5 ng/ml/h and a half life of 12.4 hours. The drug is eliminated equally via hepatic and urinary routes.

Active Ingredients

Each tablet contains 4.6 mg benazepril (equivalent to 5 mg benazepril hydrochloride). Excipients include titanium dioxide (E171), yellow iron oxide (E172), red iron oxide (E172), and black iron oxide (E172).

Indications

Treatment of heart failure in dogs. Also indicated for dogs and cats as a film coated tablet.

Dosing Guide

Follow your veterinarian's prescription.

Storage

Store as directed on packaging.

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Frequently Asked Questions — PRILBEN VET 20 MG 14 COMPRIMIDOS | TRATMIENTO DE LA INSUFICIENCIA CARDIACA EN PERROS