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LINCOSPECTIN-100 PS 150 GRS | ANTIBACTERIANO EN POLVO HIDROSOLUBLE ORAL
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LINCOSPECTIN-100 PS: Oral Antibacterial Powder for Livestock Infections

Synergistic lincomycin and spectinomycin combination for broad-spectrum bacterial control.

★★★★★ 4.41 (82 reviews)
E110
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LINCOSPECTIN-100 PS is a water-soluble oral powder for treating bacterial infections in livestock. It is active against Gram positive and Gram negative bacteria, as well as Mycoplasma, Salmonella spp., Pasteurella multocida, and Escherichia coli. The product combines lincomycin and spectinomycin for synergistic efficacy.

Spectinomycin binds to the 30S ribosomal subunit, inhibiting bacterial protein synthesis and causing misreading of the genetic code. Lincomycin binds to the 50S subunit, blocking transfer RNA coupling. Lincomycin is primarily bacteriostatic but can be bactericidal at high concentrations. After oral administration, spectinomycin reaches peak blood levels in 1 hour, while lincomycin peaks in 2 to 4 hours.

The lincomycin and spectinomycin combination shows synergistic effects at 1:1 and 1:2 ratios, resulting in greater efficacy against various pathological processes than either agent alone. Pharmacokinetic parameters of the combination are unchanged from individual active ingredients. Approximately 80% of spectinomycin is excreted unchanged in urine within 24 to 48 hours. Lincomycin is metabolized in the liver, with about 40% eliminated in feces and 5 to 10% in urine.

Active Ingredients

Each gram contains spectinomycin base (as sulfate) 667 mg and lincomycin base (as hydrochloride) 333 mg.

Indications

Treatment of infections caused by Gram positive and Gram negative bacteria, Mycoplasma, Salmonella spp., Pasteurella multocida, Escherichia coli, Staphylococcus aureus, Streptococcus spp. (beta hemolytic strains), Streptococcus viridans, Clostridium tetani, Clostridium perfringens, Erysipelothrix rhusiopathiae, and Leptospira spp. in livestock.

Dosing Guide

Follow your veterinarian's prescription.

Storage

Store as directed on packaging.

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Frequently Asked Questions — LINCOSPECTIN-100 PS 150 GRS | ANTIBACTERIANO EN POLVO HIDROSOLUBLE ORAL