SPORIMUNE 25ML | TREATMENT OF ATOPIC DERMATITIS IN DOGS

SPORIMUNE

Cyclosporine oral solution for dogs and cats

Pharmaceutical form

Oral solution (Sol.o.)

Composition per ml:

Cyclosporine 50 mg.

Indications

Dogs: Treatment of chronic manifestations of atopic dermatitis.

Cats: Symptomatic treatment of chronic allergic dermatitis

Contraindications

Do not use in case of hypersensitivity to the active substance or to any of the excipients.

Do not use in dogs under six months of age or weighing less than 2 kg.

Do not use in case of history of malignant disorders or progressive malignant disorders.

Do not vaccinate with a live vaccine during treatment or within two weeks before or after treatment.

Do not use in cats with FeLV or FIV infection.

Adverse reactions

Dogs: The occurrence of adverse reactions is uncommon.

The most frequently observed side effects are gastrointestinal disturbances such as vomiting, mucous or loose stools, and diarrhoea. They are mild and transient and do not usually require discontinuation of treatment.

Other side effects may be seen infrequently: such as lethargy or hyperactivity, anorexia, mild to moderate gingival hyperplasia, skin lesions such as warty lesions or coat changes, redness and swelling of the pinnae, muscle weakness or muscle spasms. These effects usually resolve spontaneously after discontinuation of treatment.

Diabetes mellitus has been observed very rarely and has been reported mainly in West Highland White Terriers.

Cats: In two clinical trials involving 98 cats treated with cyclosporine, the following adverse reactions were observed:

Very common: Gastrointestinal discomfort, such as vomiting or diarrhoea. These are usually moderate and transient and do not require discontinuation of treatment.

Common: Lethargy, anorexia, hypersalivation, weight loss and lymphocytopenia. These reactions usually resolve spontaneously after stopping treatment or after decreasing the frequency of the dose.

Route of administration

Orally.

Special precautions

Clinical signs of atopic dermatitis in dogs and allergic dermatitis in cats, such as itching and skin inflammation, are not specific to this disease. Allergic dermatitis in cats can present with different manifestations, including eosinophilic plaques, excoriation on the head and neck, symmetrical alopecia, and miliary dermatitis.

Any additional causes of dermatitis, such as ectoparasitic infestations, other allergies causing dermatological problems (eg, flea-bite allergy dermatitis or food allergy), or bacterial and fungal infections.

It is recommended to address flea infestations before and during the treatment of atopic dermatitis and allergic dermatitis.

A complete clinical examination should be done before administering the treatment.

Infections must be properly treated before starting treatment.

Unless serious, infections that develop during treatment should not be grounds for withdrawal of the drug.

Special attention should be paid to vaccination. The use of this veterinary medicinal product could affect the effectiveness of the vaccines. As regards inactivated vaccines, vaccination is not recommended during treatment or within two weeks before or after administration of the drug. Concomitant use of other immunosuppressants is not recommended for live vaccines.

Comments

Medicine subject to a veterinary prescription.

SPORIMUNE

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