THERIOS 300 mg 200 TABLETS FOR DOGS | Bacterial Skin Infections in Dogs

THERIOS 

2. QUALITATIVE AND QUANTITATIVE COMPOSITION
Active substance:
Each tablet contains:
Cephalexin (as cephalexin monohydrate)………………………….300 mg
For the full list of excipients, see section 6.1.
3. PHARMACEUTICAL FORM
Tablet
Beige round scored tablet.
The tablet can be divided into two or four equal parts.

4. CLINICAL DATA
4.1 Target species
Dogs
4.2 Indications for use, specifying the target species
For the treatment of bacterial skin infections in dogs (including superficial and deep pyoderma) caused by microorganisms sensitive to cephalexin.
For the treatment of urinary tract infections in dogs (including nephritis and cystitis) caused by microorganisms sensitive to cephalexin.

4.3 Contraindications
Do not use in animals hypersensitive to penicillins.
Do not use in case of severe renal insufficiency.
Do not use in rabbits, guinea pigs, hamsters and gerbils.
4.4 Special warnings for each target species
None

THERIOS 

4.8 Interaction with other medicinal products and other forms of interaction
To ensure the efficacy of the drug, do not use together with bacteriostatic antibiotics. The concomitant use of first generation cephalosporins with aminoglycoside antibiotics or with some diuretics such as furosemide may increase the risk of nephrotoxicity.

4.9 Amounts to be administered and administration route
Oral administration.
15 mg cephalexin/kg body weight, twice daily (equivalent to 30 mg/kg body weight/day) during:
– 14 days in case of urinary tract infection
– for at least 15 days in superficial infectious dermatitis.
– for at least 28 days in deep infectious dermatitis.
In severe or acute cases the dose can be safely doubled to 30 mg/kg twice daily. To adjust the dose, the tablets can be broken in half and into quarters.

To ensure correct dosing, the animal's weight should be determined as accurately as possible to avoid underdosing.
THERIOS 300 mg FLAVOR TABLETS FOR DOGS are well accepted by dogs but, if necessary, they can be crumbled and added to a small amount of food immediately before starting the usual meal.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Studies in animals experimentally administered up to 5 times the recommended dose of 15 mg/kg twice daily have shown that cephalexin is very well tolerated.
4.11 Timeout
Not applicable.

5.3 Environmental properties
Not applicable.
6. PHARMACEUTICAL DATA
6.1 List of excipients
croscamelose sodium
colloidal anhydrous silica
Magnesium stearate
dried yeast
Biscuit aroma F07012
ammonium glycyrrhizate
macro goal 6000
6.2 Incompatibilities
None known.
6.3 Validity period
Shelf-life of the veterinary medicinal product packaged for sale: 3 years
Shelf-life after opening the immediate packaging: 48 hours
Any unused portion of the tablet must be discarded after 48 hours.
6.4. Special storage precautions
Do not store at temperatures above 25°C
The unused portion of the tablet should be kept in the blister pack.
6.5 Nature and composition of immediate packaging
PVC blisters, heat-sealed with aluminum strip
Pack size:
Cardboard box with 1 blister of 10 tablets
Cardboard box with 20 blisters of 10 tablets
Not all formats may be marketed.
6.6 Special precautions for disposal of unused veterinary medicinal product or, where appropriate, residues derived from its use
Any unused veterinary medicine or residues derived from it must be disposed of in accordance with current regulations.

THERIOS 

See technical sheet