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COLMYC 25MG/ML TERNEROS SOLUCION ORAL 1L
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COLMYC 25MG/ML Oral Solution for Bacterial Infections in Poultry and Rabbits

Broad spectrum antibacterial with concentration dependent bactericidal action.

★★★★★ 3.89 (105 reviews)
E44.45
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COLMYC 25MG/ML TERNEROS SOLUCION ORAL 1L treats infections in chickens, turkeys, and rabbits caused by susceptible bacteria including Mycoplasma gallisepticum, Mycoplasma synoviae, Avibacterium paragallinarum, Pasteurella multocida, and Escherichia coli.

The active ingredient enrofloxacin exerts its bactericidal effect by interacting with the A subunit of bacterial DNA gyrase, causing irreversible degradation of chromosomal DNA and blocking replication, transcription, and recombination. This mechanism is concentration dependent. Fluoroquinolones also act on bacteria in the stationary phase by altering cell membrane permeability.

Enrofloxacin has relatively high oral bioavailability. Fluoroquinolones diffuse extensively into body fluids and tissues, reaching concentrations higher than plasma in some sites. Metabolism varies by species around 50-60 percent. Excretion is biliary and renal, with renal being predominant.

Active Ingredients

Each ml contains enrofloxacin 200 mg.

Indications

Chickens: Mycoplasma gallisepticum, Mycoplasma synoviae, Avibacterium paragallinarum, Pasteurella multocida, Escherichia coli. Turkeys: Mycoplasma gallisepticum, Mycoplasma synoviae, Pasteurella multocida, Escherichia coli. Rabbits: Treatment of respiratory infections caused by enrofloxacin susceptible Pasteurella multocida strains.

Dosing Guide

Chickens and turkeys: 10 mg enrofloxacin per kg body weight per day for 3 to 5 consecutive days (equivalent to 0.05 ml of medication per kg body weight per day). Treat for 5 consecutive days in mixed infections and chronic cases. Rabbits: 10 mg enrofloxacin per kg body weight per day for 5 days (equivalent to 0.05 ml per kg per day). Adjust concentration in drinking water based on daily consumption. Determine animal weight accurately to avoid underdosing.

Storage

Store as directed on packaging.

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Frequently Asked Questions — COLMYC 25MG/ML TERNEROS SOLUCION ORAL 1L