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COLMYC 25MG/ML TERNEROS SOLUCION ORAL 1L
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COLMYC 25MG/ML Oral Solution for Poultry and Rabbits

Broad-spectrum antibacterial for respiratory and bacterial infections in chickens, turkeys, and rabbits.

★★★★★ 4.20 (101 reviews)
E44.45
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COLMYC 25MG/ML TERNEROS SOLUCION ORAL 1L is an antibacterial oral solution indicated for chickens, turkeys, and rabbits. It treats Mycoplasma gallisepticum, Mycoplasma synoviae, Avibacterium paragallinarum, Pasteurella multocida, and Escherichia coli in chickens; Mycoplasma gallisepticum, Mycoplasma synoviae, Pasteurella multocida, and Escherichia coli in turkeys; and respiratory infections caused by Pasteurella multocida in rabbits.

Enrofloxacin exerts its bactericidal effect by interacting with the A subunit of bacterial DNA gyrase, causing irreversible degradation of chromosomal DNA and blocking replication, transcription, and recombination. This concentration-dependent mechanism also alters cell membrane permeability in stationary phase bacteria. Enrofloxacin shows relatively high oral bioavailability and extensive diffusion into body fluids and tissues, often reaching concentrations higher than plasma levels.

Metabolism varies by species, around 50-60%. Excretion occurs via bile and renal routes, with renal being predominant. Treatment duration is 3-5 consecutive days for chickens and turkeys, and 5 days for rabbits. If no clinical improvement is seen after 2-3 days, sensitivity testing should be considered.

Active Ingredients

Active ingredient: Enrofloxacin 200 mg per ml.

Indications

Chickens: Mycoplasma gallisepticum, Mycoplasma synoviae, Avibacterium paragallinarum, Pasteurella multocida, Escherichia coli. Turkeys: Mycoplasma gallisepticum, Mycoplasma synoviae, Pasteurella multocida, Escherichia coli. Rabbits: respiratory infections caused by Pasteurella multocida.

Dosing Guide

Chickens and turkeys: 10 mg enrofloxacin/kg body weight/day (0.05 ml/kg/day) for 3-5 consecutive days. For mixed infections or chronic processes, treat for 5 consecutive days. Rabbits: 10 mg enrofloxacin/kg body weight/day (0.05 ml/kg/day) for 5 days. Adjust concentration in drinking water based on daily consumption. Weigh animals accurately to avoid underdosing.

Storage

Store as directed on packaging.

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