
Amoxicillin and clavulanic acid combination for broad spectrum antibacterial action.
CLAVASEPTIN is indicated for the treatment or adjunctive treatment of periodontal infections in dogs. It contains amoxicillin (a beta lactam antibiotic) and clavulanic acid (a beta lactamase inhibitor) which together provide a broad spectrum of antibacterial activity against Gram positive and Gram negative aerobes, facultative anaerobes, and strict anaerobes, including beta lactamase producing strains.
Amoxicillin works by preventing bacterial cell wall formation, interfering with the final stage of peptidoglycan synthesis. Clavulanic acid irreversibly inhibits intracellular and extracellular beta lactamases, protecting amoxicillin from inactivation. The combination has shown efficacy against Streptococcus spp., Pasteurellaceae, Escherichia coli, and Enterobacteriaceae in canine periodontal infections.
In European studies (France, Germany, Belgium, 2002), the MIC90 values for amoxicillin/clavulanic acid (2:1 ratio) were: Streptococcus spp. 0.4/0.2 µg/ml, Pasteurellaceae 0.4/0.2 µg/ml, Escherichia coli 5.3/2.6 µg/ml, Enterobacteriaceae 22.6/11.3 µg/ml, Pseudomonadaceae 147.0/73.5 µg/ml, and Enterobacter spp. 49.6/24.8 µg/ml. Resistance is primarily mediated by beta lactamases, most common in Pseudomonadaceae (81.25%) and Enterobacter spp. (55.5%).
Each tablet contains amoxicillin (as trihydrate) 400 mg and clavulanic acid (as potassium salt) 100 mg.
For dogs: treatment or adjunctive treatment of periodontal infections. Species: dogs.
Follow your veterinarian's prescription.
Store as directed on packaging.
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CLAVASEPTIN is used to treat periodontal infections in dogs.
Amoxicillin prevents bacterial cell wall formation; clavulanic acid inhibits beta lactamases that would otherwise inactivate amoxicillin.
Side effects are not detailed in the product description. Consult your veterinarian if you observe any adverse reactions.
Administer orally as directed by your veterinarian.
Yes, as a prescription antibiotic, it requires a veterinarian prescription in Europe.
Yes, we ship to Poland, Germany, France and other EU countries.
Price varies by country and pharmacy. Please check our website for current pricing in your EU country.
Store as directed on the packaging. Keep out of reach of children and animals.
If you miss a dose, give it as soon as you remember. If it is close to the next dose, skip the missed dose. Do not double dose. Contact your veterinarian for guidance.
The bactericidal activity of amoxicillin may be reduced by simultaneous use of bacteriostatic substances such as macrolides, tetracyclines, sulfonamides, and chloramphenicol. Inform your veterinarian of all medications your pet is taking.
It is approved for dogs. No weight range is specified in the description; follow your veterinarian's dosing instructions.
Petsalia's return policy is not specified in the product description. Please contact customer service for details.
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CLAVASEPTIN is used to treat periodontal infections in dogs.
Amoxicillin prevents bacterial cell wall formation; clavulanic acid inhibits beta lactamases that would otherwise inactivate amoxicillin.
Side effects are not detailed in the product description. Consult your veterinarian if you observe any adverse reactions.
Administer orally as directed by your veterinarian.
Yes, as a prescription antibiotic, it requires a veterinarian prescription in Europe.
Yes, we ship to Poland, Germany, France and other EU countries.
Price varies by country and pharmacy. Please check our website for current pricing in your EU country.
Store as directed on the packaging. Keep out of reach of children and animals.
If you miss a dose, give it as soon as you remember. If it is close to the next dose, skip the missed dose. Do not double dose. Contact your veterinarian for guidance.
The bactericidal activity of amoxicillin may be reduced by simultaneous use of bacteriostatic substances such as macrolides, tetracyclines, sulfonamides, and chloramphenicol. Inform your veterinarian of all medications your pet is taking.
It is approved for dogs. No weight range is specified in the description; follow your veterinarian's dosing instructions.
Petsalia's return policy is not specified in the product description. Please contact customer service for details.