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CLAVASEPTIN 500MG 100 COMPRIMIDOS | ANTIBIOTICO PARA PERROS Y GATOS
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CLAVASEPTIN 500mg: Antibiotic for Periodontal Infections in Pets

Effective against beta-lactamase producing bacteria in dogs and cats.

★★★★★ 4.23 (71 reviews)
E427.67
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CLAVASEPTIN is an antibacterial tablet for dogs and cats, indicated for the treatment or adjunctive treatment of periodontal infections. It contains amoxicillin trihydrate and clavulanic acid as the potassium salt, providing a broad spectrum of activity against Gram-positive and Gram-negative aerobic, facultative anaerobic, and strict anaerobic bacteria, including beta-lactamase producing strains.

Amoxicillin is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis by interfering with peptidoglycan formation. Clavulanic acid is an irreversible inhibitor of intracellular and extracellular beta-lactamases, protecting amoxicillin from inactivation. This combination ensures efficacy against resistant bacteria.

In European studies on periodontal infections in dogs, the amoxicillin/clavulanic acid combination (2:1 ratio) showed MIC90 values of 0.4/0.2 µg/ml for Streptococcus spp. and Pasteurellaceae, 5.3/2.6 µg/ml for Escherichia coli, and 22.6/11.3 µg/ml for Enterobacteriaceae. Resistance is primarily mediated by beta-lactamases, mainly in Pseudomonadaceae (81.25%) and Enterobacter spp. (55.5%).

Active Ingredients

Each tablet contains amoxicillin trihydrate equivalent to 400 mg amoxicillin, and clavulanic acid as potassium salt equivalent to 100 mg clavulanic acid.

Indications

For dogs and cats: treatment or adjunctive treatment of periodontal infections.

Dosing Guide

Follow your veterinarian's prescription.

Storage

Store as directed on packaging.

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